Medicinal Chemistry Specialization
Students can pursue a specialization in medicinal chemistry that will prepare them for the complex and multidisciplinary approach needed for discovery of the next generation of therapeutics to fight acute and chronic disease.
The medicinal chemistry specialization requires a total of 27 credit hours, including 24 hours of graduate credit on campus as a PhD student to meet the residency requirement for the PhD. Students are admitted to PhD candidacy after having completed the residency requirement, the research tools requirement and the comprehensive written preliminary examination. After admission to candidacy, students must complete 24 hours of PHRM 600 (dissertation research) to complete the dissertation research project and prepare the dissertation document. Additional credit hours should be fulfilled with electives from SIUE or the SIU School of Medicine.
Required Courses
(4) PHPS 420 Principles of Pharmacology
(3) PHPS 500 Current Targets for Drug Discovery
(3) PHPS 501 Principles of Rational Drug Discovery
(3) CHEM 541 Advanced Organic Chemistry
(3) CHEM 551 Advanced Biochemistry
(1) PHRM 501 Introduction of Seminar (SIU School of Medicine)
(1) PHRM 500 Pharmacology Seminar (SIU School of Medicine)
(1) PHRM 540 Responsible Conduct of Research (SIU School of Medicine)
Research Tools
PhD students are required to take two of these courses (SIU School of Medicine requirement), but can take more if they choose. PHRM 552 is required for all students, CHEM 531 is required for synthetic chemistry students while CHEM 561 is required for computational chemistry students.
(3) PHRM 552 Applied Statistics for the Basic Sciences (SIU School of Medicine)
(3) CHEM 531 Advanced Analytical Chemistry
(3) CHEM 561 Advanced Physical Chemistry
(4) PHRM 551 Methods in Pharmacology (SIUE or SIU School of Medicine)
(3) MBMB 504 Research Methods (SIU School of Medicine)