Dr. Amy Hubert
Associate Professor
Ph.D. University of Wisconsin-Madison, 2008
Office: SW 1170
Research Lab: SW 1015
Phone: (618) 650-3406
E-mail: ahubert@siue.edu
Courses Taught: Genetics (BIOL 220), Developmental Biology (BIOL 425), Recombinant DNA Lab (BIOL 418B/518B), Topics in Biology of Stem Cells and regeneration (BIOL 595).
Research Interests: My lab studies the molecular biology and genetics of stem cells and regeneration in planarian flatworms. These worms have the remarkable ability to regenerate any part of their body in about one week following amputation or injury. This process relies on the function of a large pool of stem cells that can divide and differentiate to become any cell type needed to replace the missing tissues. Many genes must be turned on and off in a coordinated fashion to direct regeneration, and I am interested in how these changes in gene expression are regulated. I am currently looking at how epigenetic regulators, proteins that modify DNA or the histones it is wrapped around, function in stem cell maintenance and regeneration.
Research Opportunities: Undergraduate and graduate students interested in working in my lab should contact me.
Selected Publications
Kelly G Ross, K. Omuro, M. Taylor, R. Munday, Amy Hubert, R. King, Ricardo M Zayas. 2015. Novel monoclonal antibodies to study tissue regeneration in planarians. BMC Developmental Biology, 15, 2, www.biomedcentral.com/1471-213X/15/2.
Amy Hubert, Jordana M Henderson, Kelly G Ross, Jessica Torres, Ricardo M Zayas. 2013. Epigenetic regulation of planarian stem cells by the SET1/MLL family of histone methyltransferases. Epigenetics 8 (1): 1-13.
Martis W Cowles, Amy Hubert and Ricardo M Zayas. 2012. A Lissencephaly-1 homologue is essential for mitotic progression in the planarian Schmidtea mediterranea. Developmental Dynamics 241 (5): 901–910.
Amy M Hubert and Philip Anderson. 2009. The C. elegans sex determination gene laf-1 encodes a putative DEAD-box RNA helicase. Developmental Biology 330 (2): 358-67.
Bridget T Jacques-Fricke*, Amy M Hubert* and Sarah M Miller. 2009. A versatile module to improve understanding of scientific literature through peer instruction. Journal of College Science Teaching 39 (2): 24-32. * = equal first authors
